SCHEMBL1725816

SCHEMBL1725816

OCCCOCCOCCOCCCO

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
TSHR P16473 5/20 0.53
MAPK1 P28482 1/20 0.53
THRB P10828 1/20 0.50
HTT P42858 1/20 0.50
MAPT P10636 1/20 0.50
GAA P10253 1/20 0.39
ALDH1A1 P00352 3/20 0.35
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.32
CYP3A4 P08684 1/20 0.31
LMNA P02545 2/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4422977 1.00 MEN1 (0.60) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL15112 0.96
SCHEMBL13625481 0.93 MEN1 (0.73) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL22144196 0.93 MEN1 (0.73) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL12595181 0.93 MEN1 (0.73) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL2307153 0.93 MEN1 (0.73) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL23528602 0.92 TSHR (0.53) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL18364678 0.92 TSHR (0.53) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL5426255 0.92 TSHR (0.53) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL5671453 0.92 TSHR (0.53) MEN1KMT2ATSHRMAPK1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012034613-A3 REFRIGERATOR RED BULL GMBH (AT) 2012-05-10 WO disclosed
EP-2450998-A1 ELECTROLYTIC SOLUTION FOR CHARGEABLE DEVICE, ELECTROLYTIC SOLUTION FOR LITHIUM ION SECONDARY BATTERY, AND SECONDARY BATTERY Asahi Glass Company, Limited (JP) 2012-05-09 EP disclosed
US-20120107701-A1 ELECTROLYTE SOLUTION FOR CHARGEABLE DEVICE, ELECTROLYTE SOLUTION FOR LITHIUM ION SECONDARY BATTERY, AND SECONDARY BATTERY ASAHI GLASS COMPANY, LIMITED (JP) 2012-05-03 US disclosed
US-20120107701-A1 ELECTROLYTE SOLUTION FOR CHARGEABLE DEVICE, ELECTROLYTE SOLUTION FOR LITHIUM ION SECONDARY BATTERY, AND SECONDARY BATTERY ASAHI GLASS COMPANY, LIMITED (JP) 2012-05-03 US disclosed
EP-1329513-B1 Rapid quantitative analysis of proteins or protein function in complex mixtures UNIV WASHINGTON (US) 2011-12-07 EP disclosed
EP-1329513-B1 Rapid quantitative analysis of proteins or protein function in complex mixtures UNIV WASHINGTON (US) 2011-12-07 EP disclosed
US-7544518-B2 Rapid quantitative analysis of proteins or protein function in complex mixtures UNIVERSITY OF WASHINGTON (US) 2009-06-09 US disclosed
US-20050233399-A1 Rapid quantitative analysis of proteins or protein function in complex mixtures UNIVERSITY OF WASHINGTON 2005-10-20 US disclosed
US-6852544-B2 Rapid quantitative analysis of proteins or protein function in complex mixtures UNIVERSITY OF WASHINGTON (US) 2005-02-08 US disclosed
US-6670194-B1 Mass spectrometry; screening for changes in the expression of enzymatic activity of specific proteins induced by absence, deficiency or excess of a given protein UNIVERSITY OF WASHINGTON 2003-12-30 US disclosed
EP-1105517-B1 RAPID QUANTITATIVE ANALYSIS OF PROTEINS OR PROTEIN FUNCTION IN COMPLEX MIXTURES UNIV WASHINGTON (US) 2003-10-29 EP disclosed
EP-1329513-A1 Rapid quantitative analysis of proteins or protein function in complex mixtures UNIVERSITY OF WASHINGTON (US) 2003-07-23 EP disclosed
US-20030087322-A9 Rapid quantitative analysis of proteins or protein function in complex mixtures UNIVERSITY OF WASHINGTON 2003-05-08 US disclosed
US-20020076739-A1 Rapid quantitative analysis of proteins or protein function in complex mixtures UNIVERSITY OF WASHINGTON 2002-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020076739-A1 Rapid quantitative analysis of proteins or protein function in complex mixtures PRTN3, RPS27A, PA2G4 MEN1 2976/4885KMT2A 3934/4885TSHR 1779/4885
US-20030087322-A9 Rapid quantitative analysis of proteins or protein function in complex mixtures PRTN3, RPS27A, PA2G4 MEN1 2976/4885KMT2A 3934/4885TSHR 1779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.