Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.58 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9777956 | 0.90 | MEN1 (0.46) | TBXA2RTBXAS1HSP90AA1HSP90AB1PDK1 | |
| SCHEMBL9777943 | 0.88 | TBXA2R (0.56) | TBXA2RTBXAS1HSP90AA1HSP90AB1PDK1 | |
| SCHEMBL9778008 | 0.88 | TBXA2R (0.56) | TBXA2RTBXAS1HSP90AA1HSP90AB1PDK1 | |
| SCHEMBL9512068 | 0.85 | TBXA2R (0.63) | TBXA2RTBXAS1HSP90AA1HSP90AB1PDK1 | |
| SCHEMBL9778021 | 0.84 | TBXA2R (0.62) | TBXA2RTBXAS1HSP90AA1HSP90AB1PDK1 | |
| SCHEMBL9777999 | 0.83 | EGFR (0.47) | TBXA2RTBXAS1ALDH1A1TP53MAPT | |
| SCHEMBL9777966 | 0.81 | ALDH1A1 (0.62) | TBXA2RTBXAS1ALDH1A1MAPTPOLB | |
| SCHEMBL9777974 | 0.79 | TBXA2R (0.45) | TBXA2RTBXAS1HSP90AA1HSP90AB1PDK1 | |
| SCHEMBL9777972 | 0.78 | ALDH1A1 (0.47) | TBXA2RTBXAS1ALDH1A1TSHRCYP2C9 | |
| SCHEMBL9472791 | 0.78 | ALDH1A1 (0.63) | TBXA2RTBXAS1ALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345572-A2 | Sulfonamide derivatives, their preparation and pharmaceuticals containing them | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | claimed |
| US-4999345-A | Anticoagulants | BASF AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |
| EP-0345572-A2 | Sulfonamide derivatives, their preparation and pharmaceuticals containing them | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | disclosed |