Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778256 | 1.00 | POLB (0.46) | POLBMAPTKMT2ALMNAMEN1 | |
| SCHEMBL9778251 | 0.85 | POLB (0.46) | POLBMAPTKMT2ALMNACASP3 | |
| SCHEMBL9778255 | 0.85 | POLB (0.46) | POLBMAPTKMT2ALMNACASP3 | |
| SCHEMBL9508175 | 0.80 | AHR (0.58) | AHR | |
| SCHEMBL2388536 | 0.75 | GFER (0.46) | POLBMAPTKMT2ALMNAMEN1 | |
| SCHEMBL2388531 | 0.75 | GFER (0.46) | POLBMAPTKMT2ALMNAMEN1 | |
| SCHEMBL11827973 | 0.74 | BCHE (0.37) | AHR | |
| SCHEMBL23024872 | 0.72 | AHR (0.48) | AHRHPGD | |
| SCHEMBL5358787 | 0.72 | MAPT (0.46) | POLBMAPTKMT2ALMNAMEN1 | |
| SCHEMBL265248 | 0.70 | LMNA (0.57) | POLBMAPTKMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5036067-A | Enzyme inhibotors | MERCK & CO., INC. (US) | 1991-07-30 | — | — | US | disclosed |