Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | IDH1 | O75874 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL988885 | 0.84 | NPC1 (0.55) | NPC1RAB9ACYP1A2CYP2C19RECQL | |
| SCHEMBL9976049 | 0.82 | NPC1 (0.57) | NPC1RAB9ACYP1A2CYP2C19RECQL | |
| SCHEMBL14803687 | 0.82 | RAB9A (0.48) | NPC1RAB9ACYP1A2CYP2C19RECQL | |
| SCHEMBL9778350 | 0.82 | RAB9A (0.57) | NPC1RAB9ACYP1A2CYP2C19RECQL | |
| SCHEMBL9356623 | 0.82 | RAB9A (0.52) | NPC1RAB9ACYP1A2CYP2C19RECQL | |
| SCHEMBL23628928 | 0.82 | NPC1 (0.57) | NPC1RAB9ACYP1A2CYP2C19RECQL | |
| SCHEMBL103357 | 0.82 | RAB9A (0.76) | NPC1RAB9ACYP1A2CYP2C19RECQL | |
| SCHEMBL9712276 | 0.81 | NPC1 (0.50) | NPC1RAB9ACYP1A2CYP2C19RECQL | |
| SCHEMBL9665289 | 0.80 | NPC1 (0.49) | NPC1RAB9ACYP1A2CYP2C19RECQL | |
| SCHEMBL9712285 | 0.79 | NPC1 (0.48) | NPC1RAB9ACYP1A2CYP2C19RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075299-A | CEPHALOSPORIN COMPOUNDS AND ANTIBACTERIAL AGENTS | MEIJI SEIKA KAISHA, LTD. (JP) | 1991-12-24 | — | — | US | disclosed |
| EP-0354576-A2 | Novel cephalosporin compounds and antibacterial agents | MEIJI SEIKA KAISHA LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |