Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | CES1 | P23141 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778815 | 0.86 | TSHR (0.56) | TSHRLMNAGAACES1TDP1 | |
| SCHEMBL8389000 | 0.85 | ESR1 (0.52) | TSHRCES1CA1CA2TDP1 | |
| Terephthalamide SCHEMBL27950892 | 0.83 | TSHR (1.00) | TSHRLMNAGAACES1CA1 | |
| SCHEMBL260727 | 0.83 | TSHR (1.00) | TSHRLMNAGAACES1CA1 | |
| Hydrochloric Acid SCHEMBL11203029 | 0.81 | TSHR (0.96) | TSHRLMNAGAACES1CA1 | |
| SCHEMBL7938532 | 0.80 | ESR1 (0.64) | LMNAGAACES1CA1CA2 | |
| SCHEMBL27554215 | 0.80 | TSHR (0.85) | TSHRLMNAGAACES1CA1 | |
| Hydrochloric Acid SCHEMBL27509957 | 0.79 | TSHR (0.92) | TSHRLMNAGAACES1CA1 | |
| Methyl Alcohol SCHEMBL27858599 | 0.79 | TSHR (0.92) | TSHRLMNAGAACES1CA1 | |
| SCHEMBL9742817 | 0.79 | SRD5A2 (0.68) | TDP1ALDH1A1SMN1; SMN2MAPK1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5074891-A | Using aromatic fluorine-containing polyimide | HOECHST CELANESE CORP. (US) | 1991-12-24 | — | — | US | disclosed |
| EP-0410793-A1 | Method of gas separation and membranes therefor | HOECHST CELANESE CORPORATION (US) | 1991-01-30 | — | — | EP | disclosed |
| US-4978742-A | SOLUBLE POLYIMIDES | HOECHST CELANESE CORP. (US) | 1990-12-18 | — | — | US | disclosed |
| US-4952669-A | AND AN AROMATIC TETRACARBOXYLIC ACID; IMPROVED SOLUBILITY; MELT SPINNING; FIBERS; FILMS; COMPRESSION MOLDINGS | HOECHST CELANESE CORP. (US) | 1990-08-28 | — | — | US | disclosed |
| EP-0361413-A1 | Copolyimides prepared from 2-(3-aminophenyl)-2-(4-aminophenyl) hexafluoro propane | HOECHST CELANESE CORPORATION (US) | 1990-04-04 | — | — | EP | disclosed |
| EP-0361416-A1 | Polyamides prepared from 2-(3-aminophenyl)-2-(4-aminophenyl) hexafluoro propane | HOECHST CELANESE CORPORATION (US) | 1990-04-04 | — | — | EP | disclosed |
| EP-0361415-A1 | Polymers prepared from 2-(3-aminophenyl)-2-(4-aminophenyl) hexafluoro propane | HOECHST CELANESE CORPORATION (US) | 1990-04-04 | — | — | EP | disclosed |
| US-4914180-A | Polyamides prepared from 2-(3-aminophenyl)-2-(4-aminophenyl) hexafluoro propane | HOECHST CELANESE CORPORATION (US) | 1990-04-03 | — | — | US | disclosed |