Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | GLS | O94925 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9778893 | 0.99 | SLC2A1 (0.40) | SLC2A1GPR84CA2GLSKDM4E | |
| SCHEMBL9536888 | 0.79 | SLC2A1 (0.52) | SLC2A1KDM4EKMT2APARP14CYP1A2 | |
| SCHEMBL9529479 | 0.79 | SLC2A1 (0.46) | SLC2A1KDM4EKMT2APARP14CYP1A2 | |
| Hydrochloric Acid SCHEMBL9524680 | 0.78 | SLC2A1 (0.45) | SLC2A1KDM4EKMT2APARP14CYP1A2 | |
| SCHEMBL9779026 | 0.77 | SLC2A1 (0.37) | SLC2A1CA2 | |
| Hydrochloric Acid SCHEMBL9779215 | 0.76 | SLC2A1 (0.37) | SLC2A1 | |
| SCHEMBL9538120 | 0.74 | SLC2A1 (0.61) | SLC2A1KDM4EKMT2APARP14CYP1A2 | |
| SCHEMBL9526249 | 0.74 | SLC2A1 (0.43) | SLC2A1KDM4EMEN1KMT2APARP14 | |
| Hydrochloric Acid SCHEMBL9525885 | 0.73 | SLC2A1 (0.42) | SLC2A1MEN1KMT2APARP14CYP1A2 | |
| SCHEMBL9754468 | 0.70 | SLC2A1 (0.37) | SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999369-A | Antitumor agents | BURROUGHS WELLCOME CO. (US) | 1991-03-12 | — | — | US | claimed |
| EP-0447703-A1 | Hetero polycyclic biocidal compounds, their synthesis and intermediates therefor,formulations containing them and their use in medicine | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-25 | — | — | EP | disclosed |
| US-4999369-A | Antitumor agents | BURROUGHS WELLCOME CO. (US) | 1991-03-12 | — | — | US | disclosed |
| US-4910218-A | With a hydroxy containing secondary amine group | BURROUGHS WELLCOME CO. (US) | 1990-03-20 | — | — | US | disclosed |