Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | DBH | P09172 | 1/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 3/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.57 |
| ▸ | TUBB | P07437 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779258 | 1.00 | MAPT (0.67) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL9779565 | 0.87 | MAPT (0.67) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL9779561 | 0.87 | MAPT (0.67) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL6349920 | 0.86 | KRAS (0.74) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL6129099 | 0.86 | KRAS (0.74) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL2411839 | 0.85 | ALDH1A1 (0.66) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL10415000 | 0.85 | ALDH1A1 (0.66) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL2411836 | 0.85 | ALDH1A1 (0.66) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL9779575 | 0.85 | MAPT (0.60) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL25214553 | 0.84 | MAOB (0.72) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037824-A | Cardiotonic, antiischemic agents | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| EP-0387070-A2 | N-Containing heterocyclic compounds, processes for the preparation thereof and composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |