Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9601411 | 0.94 | LMNA (0.52) | LMNAALDH1A1MAPTMAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL9603062 | 0.93 | LMNA (0.52) | LMNAALDH1A1MAPTMAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL9873583 | 0.93 | LMNA (0.52) | LMNAALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL9779635 | 0.91 | LMNA (0.52) | LMNAALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL10339856 | 0.90 | SMN1; SMN2 (0.53) | LMNAALDH1A1MAPTHPGDKDM4E | |
| Hydrochloric Acid SCHEMBL9779403 | 0.90 | LMNA (0.52) | LMNAALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL9779606 | 0.87 | LMNA (0.49) | LMNAALDH1A1MAPTMAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL9779445 | 0.86 | LMNA (0.50) | LMNAALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL9779416 | 0.85 | KMT2A (0.52) | LMNAALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL9779411 | 0.84 | KMT2A (0.53) | LMNAALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037824-A | Cardiotonic, antiischemic agents | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| EP-0387070-A2 | N-Containing heterocyclic compounds, processes for the preparation thereof and composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |