Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765615 | 0.78 | POLB (0.39) | TDP1POLBCHRM2CHRM1CHRM3 | |
| SCHEMBL6557201 | 0.76 | CHRM2 (0.39) | TDP1POLBCHRM2CHRM1CHRM3 | |
| SCHEMBL11454286 | 0.74 | GSK3B (0.42) | TDP1POLBCHRM2CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL9779525 | 0.73 | POLB (0.39) | TDP1POLBCHRM2CHRM1CHRM3 | |
| SCHEMBL1618720 | 0.70 | CHRM2 (0.40) | GSTO1TDP1POLBCHRM2CHRM1 | |
| SCHEMBL7158576 | 0.70 | CHRM2 (0.40) | GSTO1TDP1POLBCHRM2CHRM1 | |
| SCHEMBL28938837 | 0.69 | CHRM2 (0.45) | TDP1POLBCHRM2CHRM1CHRM3 | |
| SCHEMBL28808746 | 0.66 | TSHR (0.40) | TDP1POLBDAOHPGD | |
| SCHEMBL9327532 | 0.66 | TDP1 (0.38) | TDP1POLBDAOHPGDCYP2C19 | |
| SCHEMBL8167151 | 0.65 | CPA3 (0.49) | HPGDALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015659-A | Cognition activators to slow aging of the brain | CASSELLA AKTIENGESELLSCHAFT (DE) | 1991-05-14 | — | — | US | disclosed |