Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 5/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779487 | 0.86 | CHRM1 (0.59) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL9779728 | 0.85 | CHRM1 (0.44) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL9779622 | 0.82 | CHRM1 (0.41) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL9779578 | 0.80 | CHRM1 (0.42) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL9851792 | 0.78 | CHRM1 (0.37) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL9029298 | 0.78 | CHRM1 (0.72) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL9030861 | 0.78 | CHRM1 (0.55) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL9514823 | 0.77 | CHRM1 (0.50) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL9030132 | 0.76 | CHRM1 (0.59) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL9779570 | 0.74 | CHRM1 (0.37) | CHRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411616-A1 | 4-(N-substituted amino)-2-butynyl-1-carbamates and thiocarbamates and derivatives thereof as centrally acting muscarinic agents | WARNER-LAMBERT COMPANY (US) | 1991-02-06 | — | — | EP | claimed |
| US-4996201-A | Alzheimer's disease | WARNER-LAMBERT CO. (US) | 1991-02-26 | — | — | US | disclosed |
| EP-0411616-A1 | 4-(N-substituted amino)-2-butynyl-1-carbamates and thiocarbamates and derivatives thereof as centrally acting muscarinic agents | WARNER-LAMBERT COMPANY (US) | 1991-02-06 | — | — | EP | disclosed |