Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | METAP1 | P53582 | 1/20 | 0.49 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | ROS1 | P08922 | 1/20 | 0.38 |
| ▸ | MARK3 | P27448 | 1/20 | 0.38 |
| ▸ | LTK | P29376 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2264797 | 0.89 | KMT2A (0.58) | KMT2AMEN1CASP6GFERMETAP1 | |
| SCHEMBL6162025 | 0.81 | KDM4E (0.54) | KMT2AMEN1CASP6GFERGAA | |
| Sulfuric Acid SCHEMBL19149045 | 0.80 | METAP1 (0.56) | KMT2AMEN1CASP6GFERMETAP1 | |
| SCHEMBL28126153 | 0.79 | METAP1 (0.57) | METAP1TDP2MAPTKDM4ELMNA | |
| SCHEMBL29376113 | 0.79 | METAP1 (0.57) | METAP1TDP2MAPTKDM4ELMNA | |
| SCHEMBL40823 | 0.79 | METAP1 (0.57) | METAP1TDP2MAPTKDM4ELMNA | |
| Ammonia Solution, Strong SCHEMBL28144371 | 0.77 | METAP1 (0.55) | METAP1TDP2MAPTKDM4ELMNA | |
| SCHEMBL27619851 | 0.77 | METAP1 (0.55) | METAP1TDP2MAPTKDM4ELMNA | |
| SCHEMBL4254618 | 0.75 | METAP1 (0.71) | METAP1TDP2SRD5A1SRD5A2S100A4 | |
| SCHEMBL4826135 | 0.75 | METAP1 (0.53) | METAP1TDP2MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030631-A | Hypotensive, bronchodilator agents | SCHERING CORPORATION (US) | 1991-07-09 | — | — | US | disclosed |