SCHEMBL40823

SCHEMBL40823

Brc1ccc2c(c1)Cc1cc(Br)ccc1-2

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 1/20 0.57
TDP2 O95551 1/20 0.55
PGR P06401 2/20 0.49
SRD5A1 P18405 1/20 0.48
SRD5A2 P31213 1/20 0.48
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA4 P22748 1/20 0.47
CA6 P23280 1/20 0.47
CHEK2 O96017 1/20 0.47
ROS1 P08922 1/20 0.47
MARK3 P27448 1/20 0.47
LTK P29376 1/20 0.47
FLT4 P35916 1/20 0.47
KDR P35968 1/20 0.47
MINK1 Q8N4C8 1/20 0.47
AURKB Q96GD4 1/20 0.47
PBK Q96KB5 1/20 0.47
STK17A Q9UEE5 1/20 0.47
MAP4K5 Q9Y4K4 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28126153 1.00 METAP1 (0.57) METAP1TDP2PGRSRD5A1SRD5A2
Ammonia Solution, Strong SCHEMBL28144371 0.97 METAP1 (0.55) METAP1TDP2PGRSRD5A1SRD5A2
SCHEMBL27619851 0.97 METAP1 (0.55) METAP1TDP2PGRSRD5A1SRD5A2
SCHEMBL4826135 0.95 METAP1 (0.53) METAP1TDP2PGRSRD5A1SRD5A2
SCHEMBL3129344 0.93 METAP1 (0.52) METAP1TDP2PGRSRD5A1SRD5A2
SCHEMBL415882 0.89 ALDH1A1 (0.59) METAP1TDP2SRD5A2CA1CA2
Fluorene SCHEMBL15453329 0.89 ALDH1A1 (0.59) METAP1TDP2SRD5A2CA1CA2
SCHEMBL4912147 0.89 METAP1 (0.48) METAP1TDP2PGRSRD5A1SRD5A2
Ammonia Solution, Strong SCHEMBL665105 0.87 ALDH1A1 (0.57) METAP1TDP2SRD5A2CA1CA2
SCHEMBL20233438 0.87 TDP2 (0.50) METAP1TDP2PGRSRD5A1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2319 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118221915-A Hole transport material doped with modified fluorene polymer containing oligoether chain, preparation and application thereof 华南理工大学 2024-06-21 CN claimed
CN-115521441-B Conjugated microporous polymer and preparation method and application thereof 东华理工大学 2024-05-31 CN claimed
CN-117843587-A High-quantum-yield piezochromic fluorescent material and preparation method and application thereof 山东省分析测试中心 2024-04-09 CN claimed
CN-116656061-B Heat-resistant anti-aging polyvinyl chloride cable material and preparation process thereof 双登电缆股份有限公司 2024-04-02 CN claimed
CN-117757038-A Copolymer electrolyte material and preparation method and application thereof 华东理工大学 2024-03-26 CN claimed
CN-117594772-A Graphene microsphere-based electrode material and preparation method thereof 上海博超纳烯新能源科技有限公司 2024-02-23 CN claimed
CN-115716787-B Alkyl fluorene small molecular compound and preparation method and application thereof 天津大学 2024-02-13 CN claimed
CN-117486733-A Aromatic diamine compound, preparation method and application thereof 中国科学院大连化学物理研究所 2024-02-02 CN claimed
CN-112574396-B 2-fluorophenyl fluorene and pyrrolo-pyrrole-dione copolymer photovoltaic material, preparation method and application 湖南文理学院 2023-11-03 CN claimed
CN-112592464-B Two-dimensional conjugated 2-chlorophenyl fluorene copolymer photovoltaic material, preparation method and application 湖南文理学院 2023-10-31 CN claimed
EP-1298117-B1 Method for preparing bromofluorenes JFE CHEMICAL CORP (JP) 2006-02-15 EP claimed
US-20050214568-A1 White electroluminescent polymeric material & preparation thereof CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCE 2005-09-29 US claimed
CN-1673217-A Copolymer of cationic iridium coordination compound and fluorene and its synthesis process UNIV FUDAN (CN) 2005-09-28 CN claimed
CN-1632047-A Poly-fluorene luminescent materials with carrier balance implantation and transmission and method for preparing same UNIV FUDAN (CN) 2005-06-29 CN claimed
CN-1632045-A Three-color white light macromolecule luminescent material and method for preparing same CHANGCHUN APPLIED CHEMISTRY (CN) 2005-06-29 CN claimed
CN-1594314-A Fluorene based water soluble conjugated polymer and process for preparing same UNIV FUDAN (CN) 2005-03-16 CN claimed
US-6858764-B2 Method for preparing bromofluorenes JFE CHEMICAL CORPORATION (JP) 2005-02-22 US claimed
US-20030065226-A1 Method for preparing bromofluorenes ADCHEMCO CORPORATION (JP) 2003-04-03 US claimed
EP-1298117-A2 Method for preparing bromofluorenes Adchemco Corporation (JP) 2003-04-02 EP claimed
US-5663030-A A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT XEROX CORPORATION (US) 1997-09-02 US claimed