Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 13/20 | 0.61 |
| ▸ | CYSLTR1 | Q9Y271 | 13/20 | 0.61 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARD | Q03181 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9863237 | 0.91 | CYSLTR2 (0.72) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| Water SCHEMBL9780305 | 0.90 | CYSLTR2 (0.71) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL9780320 | 0.87 | CYSLTR2 (0.82) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL9780263 | 0.87 | CYSLTR2 (0.66) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL9780224 | 0.86 | CYSLTR2 (0.65) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL10911302 | 0.85 | CYSLTR2 (0.58) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL9780479 | 0.85 | CYSLTR2 (0.84) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL9733858 | 0.84 | CYSLTR2 (0.73) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL9780157 | 0.83 | CYSLTR2 (0.67) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL9863283 | 0.82 | CYSLTR2 (0.90) | CYSLTR2CYSLTR1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990526-A | Skin disorders, antiallergens, antiinflammatory agents | MERCK FROSST CANADA, INC. (CA) | 1991-02-05 | — | — | US | disclosed |
| EP-0206741-A2 | Leukotriene antagonists | MERCK FROSST CANADA INC. (CA) | 1986-12-30 | — | — | EP | disclosed |