Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 16/20 | 0.73 |
| ▸ | CYSLTR1 | Q9Y271 | 16/20 | 0.73 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | PPARD | Q03181 | 2/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9863237 | 0.92 | CYSLTR2 (0.72) | CYSLTR2CYSLTR1GRM2PPARGPPARD | |
| Water SCHEMBL9780305 | 0.91 | CYSLTR2 (0.71) | CYSLTR2CYSLTR1GRM2PPARGPPARD | |
| SCHEMBL9780272 | 0.90 | CYSLTR2 (0.65) | CYSLTR2CYSLTR1GRM2PPARGPPARD | |
| SCHEMBL9733769 | 0.89 | CYSLTR2 (0.68) | CYSLTR2CYSLTR1GRM2PPARGPPARD | |
| SCHEMBL9734146 | 0.88 | GRM2 (0.71) | CYSLTR2CYSLTR1GRM2PPARGPPARD | |
| SCHEMBL9780281 | 0.85 | CYSLTR2 (0.82) | CYSLTR2CYSLTR1GRM2PPARGPPARD | |
| L-649923 SCHEMBL9733531 | 0.84 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1GRM2PPARGPPARD | |
| SCHEMBL9733554 | 0.84 | CYSLTR2 (0.70) | CYSLTR2CYSLTR1GRM2PPARGPPARD | |
| SCHEMBL9780238 | 0.84 | CYSLTR2 (0.61) | CYSLTR2CYSLTR1GRM2PPARGPPARD | |
| SCHEMBL9735373 | 0.84 | CYSLTR2 (0.73) | CYSLTR2CYSLTR1GRM2PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252639-A1 | Leukotriene antagonists | MERCK FROSST CANADA INC. (CA) | 1988-01-13 | — | — | EP | claimed |
| US-5135940-A | Antiallegens, antiinflammatory agents | MERCK FROSST CANADA, INC. (CA) | 1992-08-04 | — | — | US | disclosed |
| EP-0252639-A1 | Leukotriene antagonists | MERCK FROSST CANADA INC. (CA) | 1988-01-13 | — | — | EP | disclosed |