Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 11/20 | 0.57 |
| ▸ | CYSLTR1 | Q9Y271 | 11/20 | 0.57 |
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
| ▸ | PPARD | Q03181 | 4/20 | 0.51 |
| ▸ | PPARA | Q07869 | 4/20 | 0.51 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9780317 | 0.93 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL9780487 | 0.88 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL10915351 | 0.86 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL9780216 | 0.85 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL9735067 | 0.81 | CYSLTR2 (0.67) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL9780169 | 0.81 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL10893732 | 0.80 | CYSLTR2 (0.61) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL9780263 | 0.79 | CYSLTR2 (0.66) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL9780265 | 0.78 | CYSLTR2 (0.52) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL6137114 | 0.78 | PPARG (0.75) | CYSLTR2CYSLTR1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990526-A | Skin disorders, antiallergens, antiinflammatory agents | MERCK FROSST CANADA, INC. (CA) | 1991-02-05 | — | — | US | disclosed |
| EP-0206741-A2 | Leukotriene antagonists | MERCK FROSST CANADA INC. (CA) | 1986-12-30 | — | — | EP | disclosed |