Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 13/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 13/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.32 |
| ▸ | CBFB | Q13951 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9780275 | 0.91 | KCNQ3 (0.39) | KCNQ3KCNQ2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9780326 | 0.85 | KCNQ3 (0.40) | KCNQ3KCNQ2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9780565 | 0.83 | KCNQ3 (0.35) | KCNQ3KCNQ2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL1393374 | 0.80 | SMN1; SMN2 (0.41) | KCNQ3KCNQ2SMN1; SMN2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9757475 | 0.79 | SMN1; SMN2 (0.40) | KCNQ3KCNQ2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8662232 | 0.79 | SMN1; SMN2 (0.40) | KCNQ3KCNQ2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9780277 | 0.78 | KCNQ3 (0.36) | KCNQ3KCNQ2SMN1; SMN2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9757484 | 0.78 | SMN1; SMN2 (0.39) | KCNQ3KCNQ2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8660740 | 0.77 | SMN1; SMN2 (0.40) | KCNQ3KCNQ2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9780367 | 0.77 | KCNQ3 (0.35) | KCNQ3KCNQ2SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026717-A | Glutamate inhibitors | RHONE-POULENC SANTE (FR) | 1991-06-25 | — | — | US | disclosed |
| US-4980356-A | ANTICONVULSANTS; ANTISPASMODIC AGENTS; MUSCULAR AND NERVOUS SYSTEMS DISORDERS | RHONE-POULENC SANTE (FR) | 1990-12-25 | — | — | US | disclosed |