Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9780376 | 0.98 | TDP1 (0.44) | TDP1ALOX15ALOX12AKR1B1ALDH1A1 | |
| SCHEMBL165195 | 0.96 | TDP1 (0.46) | TDP1ALOX15ALOX12AKR1B1ALDH1A1 | |
| SCHEMBL29492146 | 0.81 | TDP1 (0.55) | TDP1ALOX15ALOX12AKR1B1ALDH1A1 | |
| SCHEMBL4190024 | 0.81 | TDP1 (0.55) | TDP1ALOX15ALOX12AKR1B1ALDH1A1 | |
| SCHEMBL10783026 | 0.76 | ALOX15 (0.38) | TDP1ALOX15ALOX12AKR1B1ALDH1A1 | |
| SCHEMBL752948 | 0.76 | ALOX15 (0.39) | TDP1ALOX15ALOX12AKR1B1ALDH1A1 | |
| SCHEMBL30076240 | 0.76 | ALOX15 (0.39) | TDP1ALOX15ALOX12AKR1B1ALDH1A1 | |
| SCHEMBL752753 | 0.75 | TDP1 (0.76) | TDP1ALOX15ALOX12AKR1B1 | |
| SCHEMBL9780403 | 0.74 | ALOX15 (0.42) | TDP1ALOX15ALOX12AKR1B1ALDH1A1 | |
| SCHEMBL29289454 | 0.74 | TDP1 (0.38) | TDP1ALOX15ALOX12AKR1B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981890-A | POLYHALOAROMATIC AND AROMATIC BIS-SULFONAMIDE | ETHYL CORPORATION (US) | 1991-01-01 | — | — | US | disclosed |
| US-4957957-A | Polymer compositions containing aromatic sulfonamide | ETHYL CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |