Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | GLS | O94925 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ATF4 | P18848 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5910335 | 1.00 | MEN1 (0.54) | MEN1KMT2AGLSPOLBSMN1; SMN2 | |
| SCHEMBL30873618 | 1.00 | MEN1 (0.54) | MEN1KMT2AGLSPOLBSMN1; SMN2 | |
| SCHEMBL11458128 | 0.88 | GLS (0.45) | MEN1KMT2AGLSPOLBSMN1; SMN2 | |
| SCHEMBL11172644 | 0.87 | POLB (0.47) | MEN1KMT2AGLSPOLBSMN1; SMN2 | |
| SCHEMBL2152221 | 0.85 | MEN1 (0.53) | MEN1KMT2AGLSPOLBSMN1; SMN2 | |
| SCHEMBL24193319 | 0.85 | SMN1; SMN2 (0.46) | MEN1KMT2AGLSPOLBSMN1; SMN2 | |
| SCHEMBL5847887 | 0.84 | POLB (0.48) | MEN1KMT2AGLSPOLBNFKB1 | |
| SCHEMBL5847886 | 0.84 | POLB (0.48) | MEN1KMT2AGLSPOLBNFKB1 | |
| SCHEMBL5847882 | 0.84 | POLB (0.48) | MEN1KMT2AGLSPOLBNFKB1 | |
| Hydrochloric Acid SCHEMBL11471350 | 0.83 | POLB (0.47) | MEN1KMT2AGLSPOLBNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010060-A | Method of treating herpes simplex viral infection employing pyrimidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-04-23 | — | — | US | disclosed |
| US-4851519-A | AMIDO NUCLEOSIDES, VIRICIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-07-25 | — | — | US | disclosed |