Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9780709 | 1.00 | DNMT1 (0.45) | DNMT1POLBDNMT3BADRB1 | |
| SCHEMBL9780701 | 0.92 | POLB (0.51) | DNMT1POLBDNMT3BADRB1 | |
| SCHEMBL9780708 | 0.92 | POLB (0.51) | DNMT1POLBDNMT3BADRB1 | |
| SCHEMBL25504696 | 0.83 | POLB (0.46) | DNMT1POLBADRB1 | |
| SCHEMBL9780721 | 0.83 | — | — | |
| SCHEMBL9780713 | 0.83 | — | — | |
| SCHEMBL26537753 | 0.82 | POLB (0.45) | DNMT1POLBADRB1 | |
| SCHEMBL6466613 | 0.81 | POLB (0.52) | DNMT1POLBDNMT3BADRB1 | |
| SCHEMBL5953531 | 0.81 | POLB (0.52) | DNMT1POLBDNMT3BADRB1 | |
| SCHEMBL21886710 | 0.81 | POLB (0.52) | DNMT1POLBDNMT3BADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010060-A | Method of treating herpes simplex viral infection employing pyrimidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-04-23 | — | — | US | disclosed |
| US-4851519-A | AMIDO NUCLEOSIDES, VIRICIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-07-25 | — | — | US | disclosed |