Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6704326 | 1.00 | SMN1; SMN2 (0.64) | SMN1; SMN2HPGDCYP1A2GLACYP3A4 | |
| SCHEMBL7750963 | 1.00 | SMN1; SMN2 (0.64) | SMN1; SMN2HPGDCYP1A2GLACYP3A4 | |
| SCHEMBL10691943 | 0.87 | CHRM1 (0.52) | SMN1; SMN2HPGDCYP1A2GLACYP3A4 | |
| SCHEMBL11330573 | 0.86 | TSHR (0.51) | SMN1; SMN2HPGDCYP1A2GLACYP3A4 | |
| Rac-Dichlorprop SCHEMBL3017921 | 0.86 | TSHR (0.73) | SMN1; SMN2HPGDCYP1A2GLACYP3A4 | |
| SCHEMBL8129817 | 0.86 | SMN1; SMN2 (0.64) | SMN1; SMN2HPGDCYP1A2GLACYP3A4 | |
| (R)-Dichlorprop SCHEMBL55175 | 0.86 | TSHR (0.73) | SMN1; SMN2HPGDCYP1A2GLACYP3A4 | |
| (S)-Dichlorprop SCHEMBL1535831 | 0.86 | TSHR (0.73) | SMN1; SMN2HPGDCYP1A2GLACYP3A4 | |
| Rac-Dichlorprop SCHEMBL54510 | 0.86 | TSHR (0.73) | SMN1; SMN2HPGDCYP1A2GLACYP3A4 | |
| (R)-Dichlorprop SCHEMBL29725135 | 0.86 | TSHR (0.73) | SMN1; SMN2HPGDCYP1A2GLACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010060-A | Method of treating herpes simplex viral infection employing pyrimidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-04-23 | — | — | US | disclosed |
| US-4851519-A | AMIDO NUCLEOSIDES, VIRICIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-07-25 | — | — | US | disclosed |