SCHEMBL10691943

SCHEMBL10691943

CC(Oc1ccccc1Oc1ccc(Cl)cc1Cl)C(=O)Cl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.51
MAPT P10636 3/20 0.50
PLA2G1B P04054 1/20 0.50
ATG4B Q9Y4P1 1/20 0.50
HPGD P15428 4/20 0.49
CYP1A2 P05177 1/20 0.49
GLA P06280 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
ALOX12 P18054 1/20 0.49
CYP2C19 P33261 1/20 0.49
TTR P02766 3/20 0.49
PKM P14618 1/20 0.48
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 1/20 0.48
GAA P10253 1/20 0.48
LMNA P02545 4/20 0.47
MEN1 O00255 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4179059 0.89 TSHR (0.61) CHRM1SMN1; SMN2MAPTPLA2G1BATG4B
SCHEMBL9563082 0.88 PKM (0.48) CHRM1SMN1; SMN2MAPTPLA2G1BATG4B
SCHEMBL9780720 0.87 SMN1; SMN2 (0.64) SMN1; SMN2MAPTHPGDCYP1A2GLA
SCHEMBL6704326 0.87 SMN1; SMN2 (0.64) SMN1; SMN2MAPTHPGDCYP1A2GLA
SCHEMBL7750963 0.87 SMN1; SMN2 (0.64) SMN1; SMN2MAPTHPGDCYP1A2GLA
SCHEMBL10430655 0.82 FFAR1 (0.59) SMN1; SMN2MAPTHPGDCYP1A2GLA
SCHEMBL11841315 0.81 HTR2A (0.49) MAPTMEN1KMT2ASLC6A2SLC6A3
Hydrochloric Acid SCHEMBL10694805 0.80 HPGD (0.44) CHRM1SMN1; SMN2MAPTPLA2G1BATG4B
SCHEMBL2117510 0.80 TSHR (0.64) CHRM1SMN1; SMN2MAPTHPGDCYP1A2
SCHEMBL2117939 0.78 SMN1; SMN2 (0.54) SMN1; SMN2MAPTHPGDCYP1A2GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4761175-A M-anilido-urethanes and herbicides containing these compounds BASF AKTIENGESELLSCHAFT (DE) 1988-08-02 US disclosed
EP-0021324-B1 M-ANILIDO URETHANES AND HERBICIDAL COMPOSITIONS WHICH CONTAIN THEM BASF Aktiengesellschaft (DE) 1982-01-20 EP disclosed