Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.74 |
| ▸ | PPARA | Q07869 | 4/20 | 0.74 |
| ▸ | RORC | P51449 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTR1E | P28566 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11190684 | 0.86 | PPARG (0.60) | PPARGPPARACHRM1MEN1KMT2A | |
| SCHEMBL11794321 | 0.83 | PPARA (0.59) | PPARGPPARARORCALDH1A1SLC6A2 | |
| SCHEMBL16348329 | 0.80 | PPARG (0.64) | PPARGPPARAALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL10749271 | 0.80 | PPARA (0.50) | PPARGPPARARORCALDH1A1L3MBTL1 | |
| SCHEMBL11593869 | 0.78 | PPARA (0.59) | PPARGPPARAALDH1A1TDP1SLC6A2 | |
| SCHEMBL28096041 | 0.78 | PPARA (0.59) | PPARGPPARAALDH1A1TDP1SLC6A2 | |
| SCHEMBL16348433 | 0.77 | PPARG (0.60) | PPARGPPARAALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL13374080 | 0.77 | PPARG (0.63) | PPARGPPARAALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL5644684 | 0.77 | PPARG (0.63) | PPARGPPARAALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL13374081 | 0.77 | PPARG (0.63) | PPARGPPARAALDH1A1L3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0078477-B1 | FENCLOFENAC AS TBP BLOCKING AGENT IN IODOTHYRONINE IMMUNOASSAYS | MILES LABORATORIES, INC. (US) | 1986-09-10 | — | — | EP | claimed |
| EP-0068222-B1 | PROCESS FOR THE PREPARATION OF 2-(2,4-DICHLOROPHENOXY)PHENYLACETIC ACID | Technobiotic Ltd. (CH) | 1984-09-19 | — | — | EP | claimed |
| US-4430510-A | Process for the preparation of 2-(2,4-dichlorophenoxy)-phenylacetic acid | SCHERING CORPORATION (US) | 1984-02-07 | — | — | US | claimed |
| EP-0068222-A1 | Process for the preparation of 2-(2,4-dichlorophenoxy)phenylacetic acid | Technobiotic Ltd. (CH) | 1983-01-05 | — | — | EP | claimed |
| US-4279926-A | PHENYL ALKANOIC ACID SALT OF AN AMINO ACID | SPA-SOCIETA PRODOTTI ANTIBIOTICI S.P.A. (IT) | 1981-07-21 | — | — | US | claimed |
| JP-58000932-A | — | — | None | — | — | JP | disclosed |
| CN-118556043-A | Treatment of signs, symptoms and/or complications of viral, bacterial, protozoal and/or fungal infections by highly penetrating prodrugs | 苏州泰飞尔医药有限公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-113636965-A | High penetration composition and application thereof | 于崇曦 | 2021-11-12 | — | — | CN | disclosed |
| CN-107320732-B | High penetration composition and application thereof | 于崇曦 | 2021-09-07 | — | — | CN | disclosed |
| CN-108191846-B | High penetration composition and application thereof | 于崇曦 | 2021-08-20 | — | — | CN | disclosed |
| CN-111808011-A | High penetration composition and application thereof | 于崇曦 | 2020-10-23 | — | — | CN | disclosed |
| CN-103772259-B | There is positively charged aryl and the heteroaryl acetic acid class prodrug of rapid skin penetration speed | 于崇曦 | 2016-08-31 | — | — | CN | disclosed |
| US-4077967-A | 6-Substituted penicillanic acid and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4061629-A | 6-Amino-6-arylthio penicillanic acids and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4061851-A | 7-Amino-7-arylthio cephalosporins | E. R. SQUIBB & SONS, INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4029669-A | 6-Benzalimino-6-arylthio penicillanic acids and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1977-06-14 | — | — | US | disclosed |
| US-4026886-A | 7-Acyl-7-arylthiocephalosporins | E. R. SQUIBB & SONS, INC. (US) | 1977-05-31 | — | — | US | disclosed |
| US-3965093-A | 6-Arylthio penicillanic acid and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1976-06-22 | — | — | US | disclosed |
| US-3954744-A | ANTIBACTERIAL | E. R. SQUIBB & SONS, INC. (US) | 1976-05-04 | — | — | US | disclosed |
| US-3935193-A | ANTIBIOTICS | TOYO JOZO KABUSHIKI KAISHA (JA) | 1976-01-27 | — | — | US | disclosed |