Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10448143 | 0.99 | KDM4E (0.50) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL9782036 | 0.87 | KDM4E (0.51) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL10335472 | 0.87 | KDM4E (0.51) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL9782195 | 0.86 | KDM4E (0.48) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL12879099 | 0.79 | LTA4H (0.67) | MEN1KMT2AALDH1A1ACHELTA4H | |
| SCHEMBL946497 | 0.79 | LTA4H (0.67) | MEN1KMT2AALDH1A1ACHELTA4H | |
| SCHEMBL946495 | 0.79 | LTA4H (0.67) | MEN1KMT2AALDH1A1ACHELTA4H | |
| SCHEMBL9782459 | 0.77 | POLB (0.52) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL9782179 | 0.77 | POLB (0.55) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL9782188 | 0.77 | KDM4E (0.48) | KDM4EMEN1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997836-A | Inhibitor of platelet activating factor | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-03-05 | — | — | US | disclosed |
| EP-0368670-A1 | Trisubstituted piperazine compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-05-16 | — | — | EP | disclosed |