SCHEMBL9782256

SCHEMBL9782256

COc1cc2c(cc1OC)CCCC(C(=O)N1CCN(C(=O)c3cc(OC)c(OC)c(OC)c3)C(C(=O)N(C)C)C1)=C2

nearest known ligand 0.44

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9781943 0.90 FKBP1A (0.44) POLB
SCHEMBL9782107 0.90 POLB (0.43) POLB
SCHEMBL9781982 0.87
SCHEMBL9782053 0.86 POLB (0.46) POLB
SCHEMBL9781985 0.86 POLB (0.46) POLB
SCHEMBL9782242 0.85
SCHEMBL9782319 0.84 KDM4E (0.37) POLB
SCHEMBL9782098 0.84
SCHEMBL9620863 0.84 POLB (0.58) POLB
SCHEMBL10448041 0.84 MEN1 (0.41) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4997836-A Inhibitor of platelet activating factor TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-03-05 US disclosed