Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.63 |
| ▸ | HPGD | P15428 | 8/20 | 0.63 |
| ▸ | TSHR | P16473 | 7/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.47 |
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triclofenol SCHEMBL11439326 | 0.88 | CYP3A4 (0.73) | CYP3A4MAPK1HSD17B10HPGDTSHR | |
| SCHEMBL7743436 | 0.84 | CYP3A4 (0.75) | CYP3A4MAPK1HSD17B10HPGDTSHR | |
| SCHEMBL48305 | 0.84 | HSD17B10 (0.86) | CYP3A4MAPK1HSD17B10HPGDTSHR | |
| SCHEMBL68064 | 0.84 | CYP3A4 (0.75) | CYP3A4MAPK1HSD17B10HPGDTSHR | |
| SCHEMBL31392414 | 0.84 | CYP3A4 (0.75) | CYP3A4MAPK1HSD17B10HPGDTSHR | |
| Triclofenol SCHEMBL136941 | 0.81 | CYP3A4 (0.61) | CYP3A4MAPK1HSD17B10HPGDTSHR | |
| SCHEMBL10357236 | 0.79 | HSD17B10 (0.67) | CYP3A4MAPK1HSD17B10HPGDTSHR | |
| SCHEMBL136940 | 0.79 | CYP3A4 (1.00) | CYP3A4MAPK1HSD17B10HPGDTSHR | |
| SCHEMBL8755401 | 0.78 | HSD17B10 (0.57) | CYP3A4MAPK1HSD17B10HPGDTSHR | |
| SCHEMBL592892 | 0.78 | HSD17B10 (0.75) | CYP3A4MAPK1HSD17B10HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051344-A | Iridium compounds and iron compounds in light sensitive emulsions | FUJI PHOTO FILM CO., LTD. (JP) | 1991-09-24 | — | — | US | disclosed |