Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.40 |
| ▸ | BRS3 | P32247 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | MASP2 | O00187 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9783990 | 0.84 | HPGDS (0.45) | HPGDSPDE10ABRS3PDE3BPDE3A | |
| SCHEMBL9783066 | 0.79 | TAAR1 (0.47) | NPC1NFKB1MAPK1RAB9ANFKB2 | |
| SCHEMBL9783204 | 0.74 | HPGDS (0.46) | HPGDSPDE10ABRS3MASP2 | |
| SCHEMBL9783136 | 0.73 | — | — | |
| SCHEMBL9783995 | 0.71 | HPGDS (0.45) | HPGDSPDE10ABRS3PDE3BPDE3A | |
| SCHEMBL5758643 | 0.70 | HPGDS (0.62) | HPGDSPDE10ABRS3NPY5RSCN2A | |
| SCHEMBL9783779 | 0.69 | BRS3 (0.34) | BRS3NPC1NFKB1MAPK1RAB9A | |
| SCHEMBL19339702 | 0.68 | NPC1 (0.50) | PDE10ABRS3NPC1NFKB1MAPK1 | |
| SCHEMBL9783876 | 0.68 | TAAR1 (0.52) | NPC1NFKB1MAPK1RAB9ANFKB2 | |
| SCHEMBL13960334 | 0.66 | HPGDS (0.61) | HPGDSPDE10ABRS3NPY5RSCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051514-A | Complexing boranes and imidazoles | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0432987-A2 | Fungicidal organoborane imidazole compounds and intermediates therefor | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4983589-A | Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-01-08 | — | — | US | disclosed |