Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 5/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | LDLR | P01130 | 1/20 | 0.33 |
| ▸ | ATP4A | P20648 | 2/20 | 0.32 |
| ▸ | ATP4B | P51164 | 2/20 | 0.32 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 2/20 | 0.30 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9783486 | 0.78 | PDE4A (0.37) | CYP11B1CYP11B2IDO1PCSK9 | |
| SCHEMBL9783308 | 0.76 | CYP11B1 (0.38) | CYP11B1CYP11B2IDO1PCSK9HSP90AA1 | |
| SCHEMBL9783247 | 0.75 | ATP4A (0.32) | ATP4AATP4BHCAR1GABRG2GABRB3 | |
| SCHEMBL14085646 | 0.69 | PCSK9 (0.52) | PCSK9HSP90AA1 | |
| SCHEMBL9783838 | 0.69 | CYP3A4 (0.34) | CYP11B1CYP11B2 | |
| SCHEMBL9784007 | 0.68 | PDE4A (0.36) | CYP11B1CYP11B2IDO1 | |
| SCHEMBL9784022 | 0.67 | CYP11B1 (0.40) | CYP11B1CYP11B2IDO1CRBNHPGDS | |
| SCHEMBL6663731 | 0.66 | PCSK9 (0.63) | PCSK9 | |
| SCHEMBL9783544 | 0.65 | CYP11B1 (0.36) | CYP11B1CYP11B2IDO1HPGDS | |
| SCHEMBL9783958 | 0.65 | PDE4A (0.35) | CYP11B1CYP11B2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051514-A | Complexing boranes and imidazoles | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0432987-A2 | Fungicidal organoborane imidazole compounds and intermediates therefor | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4983589-A | Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-01-08 | — | — | US | disclosed |