Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 9/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9783132 | 0.80 | TAAR1 (0.49) | CYP19A1TAAR1HRH3HRH4ALDH1A1 | |
| SCHEMBL9783866 | 0.78 | ADRA2A (0.46) | HRH3HRH4CYP1A2 | |
| SCHEMBL9783409 | 0.78 | TAAR1 (0.45) | CYP19A1TAAR1HRH3HRH4 | |
| SCHEMBL9783115 | 0.77 | TAAR1 (0.47) | CYP19A1TAAR1HRH3HRH4 | |
| SCHEMBL9783723 | 0.77 | HRH3 (0.49) | CYP19A1TAAR1HRH3HRH4 | |
| SCHEMBL233717 | 0.76 | — | — | |
| SCHEMBL9783641 | 0.75 | TAAR1 (0.46) | CYP19A1TAAR1HRH3HRH4 | |
| SCHEMBL9783961 | 0.72 | TAAR1 (0.43) | CYP19A1TAAR1HRH3HRH4 | |
| SCHEMBL21757942 | 0.72 | ORAI1 (0.41) | TAAR1LMNA | |
| SCHEMBL9783535 | 0.72 | KDM4E (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051514-A | Complexing boranes and imidazoles | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0432987-A2 | Fungicidal organoborane imidazole compounds and intermediates therefor | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4983589-A | Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-01-08 | — | — | US | disclosed |