SCHEMBL978348

SCHEMBL978348

CS(=O)(=O)N1CC=C(c2ccc(OCC3CCNCC3)cn2)CC1

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 9/20 0.54
CYP4A11 Q02928 9/20 0.54
WNT3A P56704 1/20 0.42
CYP2D6 P10635 1/20 0.42
HRH3 Q9Y5N1 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
GPR119 Q8TDV5 6/20 0.41
CCNT1 O60563 2/20 0.39
CDK9 P50750 2/20 0.39
GPR183 P32249 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1080624 0.99 CYP4F2 (0.53) CYP4F2CYP4A11WNT3ACYP2D6HRH3
SCHEMBL980281 0.86 TDP1 (0.48) CYP4F2CYP4A11CYP2D6HRH3TDP1
SCHEMBL1078144 0.85 CYP4F2 (0.52) CYP4F2CYP4A11WNT3AGPR119
SCHEMBL982179 0.84 CYP4F2 (0.50) CYP4F2CYP4A11WNT3AGPR119GPR183
SCHEMBL1092945 0.83 GPR119 (0.53) CYP4F2CYP4A11WNT3AGPR119GPR183
SCHEMBL978339 0.83 CYP4F2 (0.49) CYP4F2CYP4A11WNT3AGPR119GPR183
SCHEMBL978046 0.83 CYP4F2 (0.49) CYP4F2CYP4A11WNT3AGPR119
SCHEMBL979073 0.82 GPR119 (0.59) CYP4F2CYP4A11GPR119
SCHEMBL9947664 0.82 CYP4F2 (0.48) CYP4F2CYP4A11WNT3AGPR119GPR183
SCHEMBL981851 0.80 GPR119 (0.60) CYP4F2CYP4A11WNT3AGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8207344-B2 GPR119 agonists ELI LILLY AND COMPANY (US) 2012-06-26 US disclosed
EP-2454251-A1 GPR119 AGONISTS Eli Lilly and Company (US) 2012-05-23 EP disclosed
WO-2011008663-A1 GPR119 AGONISTS ELI LILLY AND COMPANY (US) 2011-01-20 WO disclosed
US-20110015199-A1 GPR119 Agonists ELI LILLY AND COMPANY (US) 2011-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110015199-A1 GPR119 Agonists GPR119, GLP1R, GCGR CYP4F2 1001/4885CYP4A11 510/4885WNT3A 1341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.