Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9783783 | 0.84 | CYP19A1 (0.48) | CYP19A1CYP3A4CYP17A1 | |
| SCHEMBL9783520 | 0.79 | CYP19A1 (0.42) | CYP19A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9783695 | 0.71 | CYP19A1 (0.41) | CYP19A1 | |
| SCHEMBL9783689 | 0.68 | CYP19A1 (0.34) | CYP19A1ADRA2CCYP3A4CYP1A2CYP2D6 | |
| SCHEMBL5724928 | 0.66 | HRH1 (0.55) | CYP19A1ADRA2CADRA2AADRA2BADRA1A | |
| SCHEMBL9783740 | 0.66 | CYP19A1 (0.68) | CYP19A1KCNH2HRH4 | |
| SCHEMBL9783070 | 0.65 | TAAR1 (0.49) | CYP19A1ADRA2CADRA2AADRA2BKCNH2 | |
| SCHEMBL9783847 | 0.65 | CYP3A4 (0.42) | CYP19A1CYP3A4TP53CYP2D6CYP17A1 | |
| SCHEMBL9783769 | 0.65 | PCSK9 (0.40) | CYP19A1CYP3A4CYP1A2CYP2D6CYP17A1 | |
| Dimethylamine SCHEMBL10776458 | 0.65 | CYP19A1 (0.46) | CYP19A1ADRA2CADRA2AADRA2BADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051514-A | Complexing boranes and imidazoles | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0432987-A2 | Fungicidal organoborane imidazole compounds and intermediates therefor | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4983589-A | Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-01-08 | — | — | US | disclosed |