Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 16/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9783702 | 0.84 | CYP19A1 (0.55) | CYP19A1CYP17A1CYP3A4 | |
| SCHEMBL9783740 | 0.81 | CYP19A1 (0.68) | CYP19A1 | |
| Imidazole SCHEMBL9783346 | 0.71 | HRH1 (0.44) | CYP19A1HTR2AHRH1 | |
| SCHEMBL9783847 | 0.69 | CYP3A4 (0.42) | CYP19A1CYP17A1CYP3A4 | |
| SCHEMBL9783350 | 0.69 | CYP19A1 (0.41) | CYP19A1HTR2AHRH1 | |
| SCHEMBL9783769 | 0.69 | PCSK9 (0.40) | CYP19A1CYP17A1CYP3A4 | |
| SCHEMBL9783774 | 0.68 | HRH1 (0.38) | CYP19A1HTR2AHRH1 | |
| SCHEMBL6661940 | 0.68 | HRH1 (0.61) | CYP19A1HTR2AHRH1 | |
| SCHEMBL9783836 | 0.66 | CYP3A4 (0.39) | CYP19A1CYP17A1CYP3A4 | |
| SCHEMBL2626828 | 0.65 | CYP3A4 (0.50) | CYP19A1CYP17A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051514-A | Complexing boranes and imidazoles | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0432987-A2 | Fungicidal organoborane imidazole compounds and intermediates therefor | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4983589-A | Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-01-08 | — | — | US | disclosed |