Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17395690 | 1.00 | TSHR (0.38) | TSHRTHRBMEN1KMT2AHTT | |
| SCHEMBL17395687 | 0.90 | — | — | |
| SCHEMBL5615496 | 0.90 | TSHR (0.42) | TSHRTHRBMEN1KMT2AHTT | |
| SCHEMBL8651054 | 0.90 | TSHR (0.42) | TSHRTHRBMEN1KMT2AHTT | |
| SCHEMBL5615509 | 0.90 | TSHR (0.42) | TSHRTHRBMEN1KMT2AHTT | |
| SCHEMBL5615189 | 0.90 | TSHR (0.42) | TSHRTHRBMEN1KMT2AHTT | |
| SCHEMBL5615425 | 0.90 | TSHR (0.42) | TSHRTHRBMEN1KMT2AHTT | |
| SCHEMBL5615452 | 0.90 | TSHR (0.42) | TSHRTHRBMEN1KMT2AHTT | |
| SCHEMBL5615295 | 0.90 | TSHR (0.42) | TSHRTHRBMEN1KMT2AHTT | |
| SCHEMBL1480239 | 0.87 | TSHR (0.37) | TSHRTHRBMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017221-A | Polymethylalkylsiloxane emulsions and methods | DOW CORNING CORPORATION (US) | 1991-05-21 | — | — | US | claimed |