SCHEMBL1480239

SCHEMBL1480239

CCCCC[SiH](CCCCC)O[SiH3]

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37
THRB P10828 2/20 0.37
LMNA P02545 1/20 0.32
MEN1 O00255 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
MAPT P10636 1/20 0.31
SLC22A1 O15245 2/20 0.30
SLC22A2 O15244 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5615295 0.97 TSHR (0.42) TSHRTHRBLMNAMEN1HTT
SCHEMBL5615425 0.97 TSHR (0.42) TSHRTHRBLMNAMEN1HTT
SCHEMBL8651054 0.97 TSHR (0.42) TSHRTHRBLMNAMEN1HTT
SCHEMBL5615509 0.97 TSHR (0.42) TSHRTHRBLMNAMEN1HTT
SCHEMBL5615189 0.97 TSHR (0.42) TSHRTHRBLMNAMEN1HTT
SCHEMBL5615452 0.97 TSHR (0.42) TSHRTHRBLMNAMEN1HTT
SCHEMBL5615496 0.97 TSHR (0.42) TSHRTHRBLMNAMEN1HTT
SCHEMBL9785047 0.87 TSHR (0.38) TSHRTHRBLMNAMEN1HTT
SCHEMBL17395690 0.87 TSHR (0.38) TSHRTHRBLMNAMEN1HTT
SCHEMBL17395687 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1620068-A1 COSMETIC COMPOSITION COMPRISING A VOLATILE FATTY PHASE L'OREAL (FR) 2006-02-01 EP claimed
WO-2004087077-A1 COSMETIC COMPOSITION COMPRISING A VOLATILE FATTY PHASE L'OREAL (FR) 2004-10-14 WO claimed
EP-3507104-B1 PRODUCTION OF CIS-1,4-POLYDIENES WITH MULTIPLE SILANE FUNCTIONAL GROUPS PREPARED BYIN-SITU BRIDGESTONE CORP (JP) 2024-03-27 EP disclosed
US-20230089837-A1 POLYMERIZATION PROCESSES FOR THE PRODUCTION OF CIS-1,4-POLYDIENES BRIDGESTONE CORPORATION (JP) 2023-03-23 US disclosed
US-20230038639-A1 POLYMERIZATION PROCESSES FOR THE PRODUCTION OF CIS-1,4-POLYDIENES BRIDGESTONE CORPORATION (JP) 2023-02-09 US disclosed
WO-2021133819-A1 POLYMERIZATION PROCESSES FOR THE PRODUCTION OF CIS-1,4-POLYDIENES BRIDGESTONE CORPORATION (JP) 2021-07-01 WO disclosed
WO-2021133818-A1 POLYMERIZATION PROCESSES FOR THE PRODUCTION OF CIS-1,4-POLYDIENES BRIDGESTONE CORPORATION (JP) 2021-07-01 WO disclosed
US-10975178-B2 Production of cis-1,4-polydienes with multiple silane functional groups prepared by in-situ hydrosilylation of polymer cement BRIDGESTONE CORPORATION (JP) 2021-04-13 US disclosed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
EP-2516475-B1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORP (JP) 2020-10-07 EP disclosed
US-20190211120-A1 Production Of Cis-1,4-Polydienes With Multiple Silane Functional Groups Prepared By In-Situ Hydrosilylation Of Polymer Cement BRIDGESTONE CORPORATION (JP) 2019-07-11 US disclosed
WO-2011028523-A2 PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION BRIDGESTONE CORPORATION (JP) 2011-03-10 WO disclosed
EP-1620068-A1 COSMETIC COMPOSITION COMPRISING A VOLATILE FATTY PHASE L'OREAL (FR) 2006-02-01 EP disclosed
WO-2004087077-A1 COSMETIC COMPOSITION COMPRISING A VOLATILE FATTY PHASE L'OREAL (FR) 2004-10-14 WO disclosed
US-5736471-A MONOFILAMENT WITH NAPHTHYL REPEAT UNIT ALONG THE POLYESTER BACKBONE PROVIDES A MATERIAL WITH DIMENSIONAL STABILITY, NONHYDROLYZING, ABRASION AND CHEMICAL RESISTANT; FILTERS HOECHST TREVIRA GMBH & CO KG (DE) 1998-04-07 US disclosed
US-5652057-A POLYESTER HOECHST TREVIRA GMBH & CO. KG (DE) 1997-07-29 US disclosed
EP-0102596-B1 PROCESS FOR PREPARING POLYURETHANE ELASTOMERS UTILISING DIOLS OF THE DIANHYDRO-HEXITOL-TYPE IN CONNECTION WITH POLYOXYALKYLENE-POLYDIALKYL SILOXANE COPOLYMERS BAYER AG (DE) 1988-05-11 EP disclosed
EP-0107838-A2 Polyurethane \"high-solid\" reactive coating systems incorporating a levelling agent, and their use in reactive coating BAYER AG (DE) 1984-05-09 EP disclosed
EP-0102596-A2 Process for preparing polyurethane elastomers utilising diols of the dianhydro-hexitol-type in connection with polyoxyalkylene-polydialkyl siloxane copolymers BAYER AG (DE) 1984-03-14 EP disclosed
US-4139479-A Textile treating composition THE PROCTER & GAMBLE COMPANY (US) 1979-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM TSHR 4794/4885THRB 4878/4885LMNA 455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.