Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.49 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.49 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CTH | P32929 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19745151 | 0.89 | GAA (0.50) | KAT6ATP53GAATSHRKDM4E | |
| SCHEMBL18311240 | 0.84 | KAT6A (0.60) | KAT6ATP53GAATSHRKDM4E | |
| SCHEMBL29327521 | 0.84 | GAA (0.42) | KAT6ATP53GAAALDH1A1HPGD | |
| SCHEMBL1607883 | 0.80 | GAA (0.49) | KAT6AGAATSHRKDM4EPOLB | |
| SCHEMBL12704391 | 0.79 | CYP3A4 (0.53) | KAT6AGAATSHRKDM4EPOLB | |
| SCHEMBL11095614 | 0.78 | HMGB1 (0.51) | HMGB1CXCL12PHLPP2KDM4EALDH1A1 | |
| SCHEMBL13968251 | 0.77 | HMGB1 (0.44) | HMGB1CXCL12POLBFFAR1NPC1 | |
| SCHEMBL27571808 | 0.77 | TP53 (0.43) | HMGB1CXCL12KAT6ATP53GAA | |
| SCHEMBL3954125 | 0.76 | TP53 (0.54) | HMGB1CXCL12TP53GAATSHR | |
| SCHEMBL16406152 | 0.75 | HMGB1 (0.40) | HMGB1CXCL12KAT6ATP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017042557-A1 | GLYCOMIMETICS FOR USE FOR THE TREATMENT OF VASCULAR CALCIFICATION AND/OR ENDOTHELIAL DYSFUNCTION | MANCHESTER METROPOLITAN UNIVERSITY (GB) | 2017-03-16 | — | — | WO | disclosed |
| US-5057143-A | Herbicides, plant growth regulators | BASF AKTIENGESELLSCHAFT (DE) | 1991-10-15 | — | — | US | disclosed |