Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.51 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | PTPRB | P23467 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | OGG1 | O15527 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP9 | P55211 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CTH | P32929 | 1/20 | 0.38 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13883592 | 0.86 | HPGD (0.49) | HPGDHSD17B10PTPRBTHRATHRB | |
| SCHEMBL9785087 | 0.78 | HMGB1 (0.49) | HMGB1CXCL12HPGDHSD17B10THRA | |
| SCHEMBL4400139 | 0.78 | HMGB1 (0.55) | HMGB1CXCL12HPGDHSD17B10ALDH1A1 | |
| SCHEMBL13965398 | 0.77 | MEN1 (0.56) | HMGB1CXCL12MCL1CYP1A2CYP2C9 | |
| SCHEMBL19745145 | 0.75 | ALOX15 (0.50) | HPGDHSD17B10PTPRBTHRATHRB | |
| SCHEMBL6516217 | 0.75 | HPGD (0.62) | HPGDHSD17B10PTPRBTHRATHRB | |
| SCHEMBL15615389 | 0.75 | RXRA (0.55) | HMGB1CXCL12THRATHRBALDH1A1 | |
| SCHEMBL8402084 | 0.75 | ALDH1A1 (0.56) | HPGDHSD17B10ALDH1A1KDM4EMCL1 | |
| SCHEMBL25528227 | 0.73 | HPGD (0.50) | HPGDHSD17B10PTPRBTHRATHRB | |
| SCHEMBL10420488 | 0.72 | MAPT (0.46) | HMGB1CXCL12CASP3CASP7CASP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460580-A | N-Alkylated aminoalcohols and their pharmaceutical compositions useful for the treatment of cardiac insufficiency | CIBA-GEIGY CORPORATION (US) | 1984-07-17 | — | — | US | disclosed |