Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9785297 | 0.91 | CYP19A1 (0.43) | POLBHPGDKMT2AKDM4EALDH1A1 | |
| SCHEMBL9785238 | 0.89 | POLB (0.41) | POLBHPGDKCNH2KMT2AKDM4E | |
| SCHEMBL29622918 | 0.88 | ADRA2C (0.45) | POLBHPGDKMT2AKDM4EALDH1A1 | |
| SCHEMBL9785351 | 0.88 | ADRA2C (0.45) | POLBHPGDKMT2AKDM4EALDH1A1 | |
| SCHEMBL9785350 | 0.86 | POLB (0.41) | POLBHPGDKMT2AKDM4EALDH1A1 | |
| SCHEMBL9785251 | 0.86 | POLB (0.41) | POLBHPGDKMT2AKDM4EALDH1A1 | |
| SCHEMBL15756589 | 0.84 | CYP19A1 (0.40) | POLBHPGDKDM4EALDH1A1TSHR | |
| SCHEMBL9785252 | 0.84 | KMT2A (0.41) | POLBHPGDKCNH2KMT2AKDM4E | |
| SCHEMBL11182570 | 0.82 | POLB (0.43) | POLBHPGDKMT2AKDM4EALDH1A1 | |
| SCHEMBL18542636 | 0.81 | POLB (0.41) | POLBHPGDKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992458-A | Phytofungicides | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| EP-0275955-B1 | MICROBICIDAL COMPOSITION | CIBA-GEIGY AG (CH) | 1990-07-04 | — | — | EP | disclosed |
| EP-0275955-A1 | Microbicidal composition | CIBA-GEIGY AG (CH) | 1988-07-27 | — | — | EP | disclosed |