Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | CYP2J2 | P51589 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9786953 | 1.00 | HRH1 (0.48) | HRH1BCHECYP2J2KCNH2PAX8 | |
| SCHEMBL9787022 | 1.00 | HRH1 (0.48) | HRH1BCHECYP2J2KCNH2PAX8 | |
| SCHEMBL9786973 | 0.99 | HRH1 (0.49) | HRH1BCHECYP2J2KCNH2PAX8 | |
| Oxalic Acid SCHEMBL9787012 | 0.96 | HRH1 (0.48) | HRH1BCHECYP2J2KCNH2PAX8 | |
| SCHEMBL9786906 | 0.96 | PAX8 (0.48) | HRH1CYP2J2KCNH2PAX8 | |
| SCHEMBL9786980 | 0.91 | HRH1 (0.44) | HRH1CYP2J2KCNH2PAX8 | |
| Hydrochloric Acid SCHEMBL9787237 | 0.89 | HRH1 (0.43) | HRH1CYP2J2PAX8 | |
| SCHEMBL9786834 | 0.85 | CYP2J2 (0.46) | HRH1BCHECYP2J2KCNH2PAX8 | |
| SCHEMBL9786892 | 0.84 | CYP2J2 (0.59) | HRH1CYP2J2KCNH2PAX8 | |
| SCHEMBL9874017 | 0.84 | CYP2J2 (0.51) | HRH1CYP2J2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063235-A | 4-[(diaryl)hydromethyl]-1-piperidinealkanols and esters and carbamates thereof useful in the treatment of allergic disorders | A. H. ROBINS COMPANY, INC. (US) | 1991-11-05 | — | — | US | claimed |