Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.82 |
| ▸ | TSHR | P16473 | 4/20 | 0.82 |
| ▸ | LMNA | P02545 | 2/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.79 |
| ▸ | TP53 | P04637 | 1/20 | 0.79 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL28088267 | 1.00 | ALDH1A1 (0.82) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| Palmitic Acid SCHEMBL28150013 | 1.00 | ALDH1A1 (0.82) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| Sebacic Acid SCHEMBL27848500 | 1.00 | ALDH1A1 (0.82) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| Adipic Acid SCHEMBL5539742 | 1.00 | ALDH1A1 (0.82) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| Sebacic Acid SCHEMBL28015861 | 1.00 | ALDH1A1 (0.82) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| Stearic Acid SCHEMBL29289372 | 0.98 | ALDH1A1 (0.79) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| Dibutyl Phthalate SCHEMBL14976820 | 0.97 | ALDH1A1 (0.77) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| Glutarate SCHEMBL27844901 | 0.97 | ALDH1A1 (0.82) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| Succinic Acid SCHEMBL27501685 | 0.95 | ALDH1A1 (0.84) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| Succinic Acid SCHEMBL11488049 | 0.95 | ALDH1A1 (0.84) | ALDH1A1TSHRLMNACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE33761-E | HIGH COMPATIBILITY WITH CABLE GREASES OR FILLERS | CASCHEM, INC. (US) | 1991-12-03 | — | — | US | disclosed |