Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 13/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.58 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787764 | 0.90 | ADRB3 (0.54) | ADRB3ADRB2ADRB1SLC2A1CYP2D6 | |
| SCHEMBL9787723 | 0.89 | ACACB (0.51) | ADRB3ADRB2ADRB1SLC2A1CYP2D6 | |
| Oxalic Acid SCHEMBL9787777 | 0.88 | ADRB3 (0.59) | ADRB3ADRB2ADRB1SLC2A1CYP2D6 | |
| Alcohol SCHEMBL9787714 | 0.85 | ACACB (0.48) | ADRB3ADRB2ADRB1SLC2A1CYP2D6 | |
| SCHEMBL9787809 | 0.85 | ADRB3 (0.51) | ADRB3ADRB1 | |
| SCHEMBL10433629 | 0.82 | ADRB3 (0.81) | ADRB3ADRB2ADRB1SLC2A1CYP2D6 | |
| Alcohol SCHEMBL9787806 | 0.80 | ADRB3 (0.50) | ADRB3ADRB1 | |
| Oxalic Acid SCHEMBL9787760 | 0.79 | ADRB3 (0.56) | ADRB3ADRB2ADRB1SLC2A1CYP2D6 | |
| SCHEMBL10775626 | 0.79 | ADRB3 (0.86) | ADRB3ADRB2ADRB1SLC2A1CYP2D6 | |
| Oxalic Acid SCHEMBL9787718 | 0.78 | ACACB (0.52) | ADRB3ADRB2ADRB1SLC2A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045567-A | Propanolamine derivatives having anti-diabetic effects | HOFFMANN-LA ROCHE INC. (US) | 1991-09-03 | — | — | US | disclosed |