Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.32 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7602761 | 1.00 | LMNA (0.39) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL8022107 | 0.95 | LMNA (0.36) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL8035792 | 0.95 | LMNA (0.36) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL8038264 | 0.95 | LMNA (0.36) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL8038172 | 0.95 | LMNA (0.36) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL8032050 | 0.95 | LMNA (0.36) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL8031914 | 0.95 | LMNA (0.36) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL9787947 | 0.92 | MEN1 (0.39) | MEN1KMT2AALDH1A1GBA1CYP1A2 | |
| SCHEMBL11138036 | 0.92 | MEN1 (0.39) | MEN1KMT2AALDH1A1GBA1CYP1A2 | |
| SCHEMBL4665795 | 0.92 | MEN1 (0.39) | MEN1KMT2AALDH1A1GBA1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030629-A | Transdermal Administration Of Cardiovascular Agents | THERAPEUTIC PATCH RESEARCH N.V. | 1991-07-09 | — | — | US | disclosed |