Methacrylic Acid

Methacrylic Acid

SCHEMBL9788015

C=C(C)C(=O)O.C=C(C)C(=O)OCCS(=O)(=O)O

nearest known ligand 0.47

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Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.47
TSHR P16473 3/20 0.46
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 2/20 0.37
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL7540011 0.96 THRB (0.44) THRBTSHRPOLBAPEX1HTT
SCHEMBL14895 0.94 THRB (0.52) THRBTSHRPOLBAPEX1HTT
Lithium SCHEMBL31305329 0.92 THRB (0.50) THRBTSHRPOLBAPEX1HTT
SCHEMBL8861523 0.92 THRB (0.50) THRBTSHRPOLBAPEX1HTT
SCHEMBL434886 0.92 THRB (0.50) THRBTSHRPOLBAPEX1HTT
SCHEMBL1303200 0.92 THRB (0.50) THRBTSHRPOLBAPEX1HTT
SCHEMBL8861467 0.92 THRB (0.50) THRBTSHRPOLBAPEX1HTT
Methane SCHEMBL8400058 0.92 THRB (0.50) THRBTSHRPOLBAPEX1HTT
Ammonia Solution, Strong SCHEMBL1252864 0.92 THRB (0.50) THRBTSHRPOLBAPEX1HTT
SCHEMBL8861435 0.92 THRB (0.50) THRBTSHRPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5075399-A Highly absorbent to aqueous electrolyte solutions PHILLIPS PETROLEUM COMPANY (US) 1991-12-24 US claimed
CN-112368029-A Systems and methods for removing preservatives from ophthalmic formulations containing complexing agents 特清公司 2021-02-12 CN disclosed
US-4071508-A SIMULTANEOUS POLYMERIZATION PLASTOMEDICAL SCIENCES, INC. (US) 1978-01-31 US disclosed