SCHEMBL978822

SCHEMBL978822

CCCCC(C)CCC[O]

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ACE2 Q9BYF1 1/20 0.45
LMNA P02545 1/20 0.39
DNM1 Q05193 2/20 0.38
TSHR P16473 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
FDPS P14324 1/20 0.37
MAPT P10636 1/20 0.36
OPRM1 P35372 1/20 0.36
CA2 P00918 2/20 0.36
MAPK1 P28482 1/20 0.36
CA1 P00915 2/20 0.34
ALDH1A1 P00352 2/20 0.33
TP53 P04637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
SLC15A1 P46059 1/20 0.33
BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL980761 0.92 ACE2 (0.54) ACE2LMNAFDPSMAPTOPRM1
SCHEMBL978906 0.92 ACE2 (0.48) ACE2LMNADNM1TSHRSMN1; SMN2
SCHEMBL7781562 0.90 ACE2 (0.52) ACE2LMNADNM1FDPSOPRM1
SCHEMBL28025529 0.90 ACE2 (0.57) ACE2LMNADNM1TSHRFDPS
SCHEMBL28025470 0.90 ACE2 (0.57) ACE2LMNADNM1TSHRFDPS
SCHEMBL7776283 0.90 ACE2 (0.52) ACE2LMNADNM1FDPSOPRM1
SCHEMBL7782859 0.90 ACE2 (0.52) ACE2LMNADNM1FDPSOPRM1
SCHEMBL28025558 0.90 ACE2 (0.57) ACE2LMNADNM1TSHRFDPS
SCHEMBL22749072 0.90 ACE2 (0.57) ACE2LMNADNM1TSHRFDPS
SCHEMBL27394455 0.90 ACE2 (0.57) ACE2LMNADNM1TSHRFDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023223888-A1 METHOD FOR PRODUCING POLYCARBONATE RESIN, AND ALICYCLIC POLYCARBONATE RESIN 旭化成株式会社 2023-11-23 WO disclosed
US-20230159727-A1 STERICALLY HINDERED AMINE STABILIZER MIXTURES BASF SE (DE) 2023-05-25 US disclosed
EP-3935052-A1 STERICALLY HINDERED AMINE STABILIZER MIXTURES BASF SE (DE) 2022-01-12 EP disclosed
CN-113544126-A Hindered amine stabilizer mixtures 巴斯夫欧洲公司 2021-10-22 CN disclosed
CN-109721723-B Surfactant, method for producing the same, and solution containing the same 中日合成化学股份有限公司 2021-07-06 CN disclosed
WO-2020182587-A1 STERICALLY HINDERED AMINE STABILIZER MIXTURES BASF SE (DE) 2020-09-17 WO disclosed
EP-3191471-B1 4,5-DIHYDROPYRAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY ABBVIE DEUTSCHLAND (DE) 2020-03-11 EP disclosed
US-9944623-B2 Sterically hindered amine stabilizer BASF SE (DE) 2018-04-17 US disclosed
EP-2475655-B1 STERICALLY HINDERED AMINE STABILIZER BASF SE (DE) 2017-10-11 EP disclosed
EP-3191471-A1 4,5-DIHYDROPYRAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY AbbVie Deutschland GmbH & Co. KG (DE) 2017-07-19 EP disclosed
EP-1209166-A1 NOVEL A-500359 DERIVATIVES Sankyo Company, Limited (JP) 2002-05-29 EP disclosed
EP-1201632-A1 FUSED RING COMPOUND DAINIPPON INK AND CHEMICALS, INC. (JP) 2002-05-02 EP disclosed
EP-0763524-B1 Urea and amide derivatives having ACAT inhibitory activity, their preparation and their therapeutic and prophylactic use SANKYO CO (JP) 2000-08-23 EP disclosed
US-6040339-A TREATMENT AND PROPHYLAXIS OF HYPERCHOLESTEREMIA OR ARTERIOSCLEROSIS IN A MAMMAL SANKYO COMPANY, LIMITED (JP) 2000-03-21 US disclosed
US-5880147-A Amide derivatives having ACAT inhibitory activity, their preparation and their therapeutic and prohylactic use SANKYO COMPANY, LIMITED (JP) 1999-03-09 US disclosed
US-5691319-A ANTICARCINOGENIC AGENTS SANKYO COMPANY, LIMITED (JP) 1997-11-25 US disclosed
EP-0763524-A1 Urea and amide derivatives having ACAT inhibitory activity, their preparation and their therapeutic and prophylactic use SANKYO COMPANY LIMITED (JP) 1997-03-19 EP disclosed
EP-0536936-B1 Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use SANKYO CO (JP) 1996-08-14 EP disclosed
EP-0536936-A1 Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use Sankyo Company Limited (JP) 1993-04-14 EP disclosed
US-4859759-A Siloxane containing benzotriazolyl/tetraalkylpiperidyl substituent KIMBERLY-CLARK CORPORATION (US) 1989-08-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159727-A1 STERICALLY HINDERED AMINE STABILIZER MIXTURES PYM1, H1-4, C5 ACE2 2494/4885LMNA 2637/4885DNM1 1273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.