Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFB | P00751 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 8/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 6/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788276 | 0.87 | CFB (0.46) | CFBTAAR1ADRA2AADRA1AADRA2B | |
| SCHEMBL9788345 | 0.84 | CFB (0.55) | CFBTAAR1ADRA2AADRA1AADRA2B | |
| SCHEMBL9788340 | 0.83 | CFB (0.50) | CFBTAAR1ADRA2AADRA1AADRA2B | |
| SCHEMBL9788308 | 0.83 | CFB (0.53) | CFBTAAR1ADRA2AADRA1AADRA2B | |
| SCHEMBL9788332 | 0.80 | CFB (0.50) | CFBTAAR1ADRA2AADRA1AADRA2B | |
| SCHEMBL11440748 | 0.79 | TAAR1 (0.75) | CFBTAAR1ADRA2AADRA1AADRA2B | |
| SCHEMBL7047294 | 0.76 | CFB (0.50) | CFBTAAR1ADRA2AADRA1AADRA2B | |
| SCHEMBL9788311 | 0.76 | TAAR1 (0.55) | CFBTAAR1ADRA2AADRA1AADRA2B | |
| SCHEMBL7048730 | 0.75 | TAAR1 (0.60) | CFBTAAR1ADRA2AADRA1AADRA2B | |
| SCHEMBL9788278 | 0.73 | CFB (0.44) | CFBTAAR1ADRA2AADRA1AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066664-A | Control of intraocular bleeding and pressure | ALLERGAN, INC. (US) | 1991-11-19 | — | — | US | disclosed |