Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFB | P00751 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.47 |
| ▸ | CBFB | Q13951 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | TNIK | Q9UKE5 | 10/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788327 | 0.83 | CFB (0.54) | CFBTAAR1MAPTGAAKDM4E | |
| SCHEMBL9788271 | 0.81 | TNIK (0.45) | CFBTAAR1ADRA2AADRA1AADRA2B | |
| SCHEMBL9788325 | 0.79 | ADRA2A (0.40) | CFBTAAR1GAAADRA2AADRA1A | |
| SCHEMBL9788291 | 0.79 | TAAR1 (0.45) | CFBTAAR1ADRA2AADRA1AADRA2B | |
| SCHEMBL7047648 | 0.78 | TAAR1 (0.56) | CFBTAAR1MAPTKDM4EALDH1A1 | |
| SCHEMBL9788328 | 0.77 | ADRA2A (0.45) | CFBTAAR1MAPTGAAALDH1A1 | |
| SCHEMBL7044957 | 0.76 | TAAR1 (0.48) | CFBTAAR1ADRA2AADRA1AADRA2B | |
| SCHEMBL9788317 | 0.76 | CFB (0.44) | CFBTAAR1ADRA2AADRA1AADRA2B | |
| SCHEMBL9788278 | 0.76 | CFB (0.44) | CFBTAAR1ADRA2AADRA1AADRA2B | |
| SCHEMBL9788287 | 0.74 | CFB (0.40) | CFBTAAR1MAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066664-A | Control of intraocular bleeding and pressure | ALLERGAN, INC. (US) | 1991-11-19 | — | — | US | disclosed |