SCHEMBL9788451

SCHEMBL9788451

CC(C)=CCc1c(O)cc(C)cc1O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.69
BACE1 P56817 1/20 0.69
CYP19A1 P11511 5/20 0.58
MAOB P27338 5/20 0.56
MAOA P21397 1/20 0.56
ALOX5 P09917 3/20 0.49
PTGS2 P35354 3/20 0.49
HPGD P15428 1/20 0.46
APP P05067 2/20 0.46
ALOX15 P16050 1/20 0.45
ALOX12 P18054 1/20 0.45
XDH P47989 1/20 0.45
PDE4B Q07343 1/20 0.45
PDE4D Q08499 1/20 0.45
OSBP P22059 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
PPARG P37231 4/20 0.43
PPARA Q07869 3/20 0.43
TRPA1 O75762 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24804443 0.90 PTPN1 (0.58) PTPN1BACE1CYP19A1MAOBMAOA
SCHEMBL5932059 0.84 MAOB (0.62) PTPN1BACE1CYP19A1MAOBMAOA
SCHEMBL19846964 0.84 PTPN1 (0.97) PTPN1BACE1MAOBALOX5PTGS2
SCHEMBL23522862 0.84 PTPN1 (0.97) PTPN1BACE1MAOBALOX5PTGS2
Grifolin SCHEMBL8589594 0.82 PTPN1 (1.00) PTPN1BACE1MAOBALOX5PTGS2
Grifolin SCHEMBL21065400 0.82 PTPN1 (1.00) PTPN1BACE1MAOBALOX5PTGS2
SCHEMBL21180310 0.82 PTPN1 (0.63) PTPN1BACE1CYP19A1MAOBMAOA
SCHEMBL15361658 0.80 CYP19A1 (0.59) PTPN1BACE1CYP19A1MAOBMAOA
SCHEMBL31545116 0.79 MAOB (0.53) PTPN1BACE1CYP19A1MAOBMAOA
SCHEMBL17208346 0.79 ALOX15 (0.51) PTPN1BACE1CYP19A1MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3284612-A None JP disclosed
US-20250090554-A1 A METHOD OF TREATING DEPRESSION BY IMMUNE MODULATION MYND LIFE SCIENCES INC (CA) 2025-03-20 US disclosed
JP-H03284612-A TYROSINASE ACTIVITY INHIBITOR, ANTIOXIDANT AND ANTIMICROBIAL AGENT NARISU KESHOHIN:KK 1991-12-16 JP disclosed