Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PPIA | P62937 | 2/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5351687 | 0.88 | HPGD (0.52) | MEN1KMT2AMAOBPOLBMRGPRX4 | |
| SCHEMBL10527100 | 0.86 | MAOB (0.52) | MEN1KMT2AMAOBMAOACA12 | |
| SCHEMBL10390521 | 0.85 | GRIN2D (0.57) | MEN1KMT2AMAOBPOLBMRGPRX4 | |
| SCHEMBL19821457 | 0.83 | MEN1 (0.54) | MEN1KMT2AHSP90AA1MAOBPPIA | |
| SCHEMBL1681414 | 0.82 | KMT2A (0.53) | MEN1KMT2AHSP90AA1POLBMRGPRX4 | |
| SCHEMBL10391523 | 0.81 | KMT2A (0.49) | MEN1KMT2AHSP90AA1MAOBPOLB | |
| SCHEMBL10421184 | 0.80 | MCL1 (0.57) | MAOBMRGPRX4 | |
| SCHEMBL8118387 | 0.80 | MAOA (0.60) | MEN1KMT2AHSP90AA1MAOBMAOA | |
| SCHEMBL11168197 | 0.79 | MRGPRX4 (0.54) | MAOBMRGPRX4 | |
| SCHEMBL8123886 | 0.79 | TDP1 (0.61) | MEN1KMT2APOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015663-A | Treatment of conditions requiring enhanced oxygen availability of mammalian tissues | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-05-14 | — | — | US | disclosed |
| US-4948582-A | PRETREATMENT WITH AN OXYNAPHTHOIC ACID DERIVATIVE | RORER PHARMACEUTICAL CORPORATION (US) | 1990-08-14 | — | — | US | disclosed |
| EP-0347932-A2 | Treatment of conditions requiring enhanced oxygen availability to mammalian tissues | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1989-12-27 | — | — | EP | disclosed |
| US-4861795-A | USING NAPHTHOIC ACID DERIVATIVE | RORER PHARMACEUTICAL CORPORATION (US) | 1989-08-29 | — | — | US | disclosed |