Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL11794048 | 1.00 | TSHR (0.50) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Ethylene Glycol SCHEMBL16714231 | 0.94 | TSHR (0.44) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| 2-Chloroethanol SCHEMBL11553025 | 0.93 | TSHR (0.50) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL9447825 | 0.90 | TSHR (0.67) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL9111 | 0.90 | — | — | |
| Triethylene Glycol SCHEMBL9447828 | 0.87 | MEN1 (0.69) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL315062 | 0.87 | MEN1 (0.69) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL2474236 | 0.87 | MEN1 (0.69) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL3861837 | 0.87 | MEN1 (0.69) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL2477057 | 0.87 | MEN1 (0.69) | TSHRMAPK1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015754-A | Cationic polyethers for fixing reative and direct dyes used for dyeing and printing cellulose textiles; washfastness | BASF AKTIENGESELLSCHAFT (DE) | 1991-05-14 | — | — | US | disclosed |
| US-4775384-A | Process for treating fibre materials | BAYER AKTIENGESELLSCHAFT (DE) | 1988-10-04 | — | — | US | disclosed |
| US-4737576-A | Basic polycondensates | BAYER AKTIENGESELLSCHAFT (DE) | 1988-04-12 | — | — | US | disclosed |
| US-4238620-A | ANTIPYRETICS; ANALGESICS; ANTIINFLAMMATORY AGENTS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1980-12-09 | — | — | US | disclosed |
| EP-0003893-A1 | Novel dibenz (b,f) oxepin and dibenzo (b,f) thiepin compounds and pharmaceutically acceptable salts thereof, processes for their preparation and pharmaceutical compositions containing them | Dainippon Pharmaceutical Co., Ltd. (JP) | 1979-09-05 | — | — | EP | disclosed |