Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | MMP12 | P39900 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788724 | 0.95 | ALDH1A1 (0.68) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL29687907 | 0.84 | ALDH1A1 (1.00) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL116566 | 0.84 | ALDH1A1 (1.00) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL4528251 | 0.83 | ALDH1A1 (0.58) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL9057293 | 0.82 | ALDH1A1 (0.96) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL12114030 | 0.82 | ALDH1A1 (0.77) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL3424984 | 0.82 | ALDH1A1 (0.96) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL30449714 | 0.82 | ALDH1A1 (0.57) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL29388715 | 0.81 | ALDH1A1 (0.89) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL50441 | 0.81 | ALDH1A1 (0.89) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019068820-A1 | PESTICIDALLY ACTIVE PYRROLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-04-11 | — | — | WO | disclosed |
| US-5075452-A | PROCESS FOR THE PREPARATION OF 5-MEMBERED NITROGEN CONTAINING HETEROAROMATICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-12-24 | — | — | US | disclosed |