Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3561504 | 0.77 | TSHR (0.53) | GAAALDH1A1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL9788830 | 0.76 | ACHE (0.46) | GAA | |
| SCHEMBL6268216 | 0.73 | MAPK1 (0.54) | ALDH1A1HPGDMAPTSMN1; SMN2TSHR | |
| SCHEMBL13103676 | 0.72 | HDAC1 (0.48) | GAAALDH1A1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL11526113 | 0.72 | HPGD (0.56) | GAAALDH1A1HPGDMAPTAPOBEC3A | |
| SCHEMBL1395778 | 0.71 | CYP3A4 (0.68) | ALDH1A1CYP3A4CYP1A2CYP2C19HPGD | |
| SCHEMBL9711270 | 0.71 | CYP3A4 (0.68) | GAAALDH1A1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL11693746 | 0.71 | HRH2 (0.55) | CYP3A4CYP1A2MAPTTAAR1MEN1 | |
| SCHEMBL5189643 | 0.71 | HDAC1 (0.63) | ALDH1A1CYP3A4CYP1A2CYP2C19TAAR1 | |
| SCHEMBL108372 | 0.70 | TAAR1 (0.58) | GAAALDH1A1CYP3A4CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030738-A | Synthesis of antiulcer compounds | JANUS FARMACEUTICI S.R.L. (IT) | 1991-07-09 | — | — | US | disclosed |