Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9625908 | 0.88 | KDM4E (0.69) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL12227223 | 0.88 | KDM4E (0.64) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL5085750 | 0.86 | ALDH1A1 (0.54) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL173232 | 0.86 | KDM4E (0.54) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL9626411 | 0.86 | KDM4E (0.67) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL9625662 | 0.86 | KDM4E (0.67) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL9627195 | 0.86 | KDM4E (0.67) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL9625872 | 0.86 | KDM4E (0.67) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL3255815 | 0.84 | ALDH1A1 (0.56) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL7901091 | 0.84 | ALDH1A1 (0.55) | KDM4EALDH1A1HTR1AADRA2CADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0054488-B1 | USE OF DI(ALKYLPHENOXY) METHANES AS ISOLATING OILS, AND DI(ALKYLPHENOXY) METHANE WHICH CAN BE USED FOR THIS APPLICATION | COMPAGNIE FRANCAISE DE RAFFINAGE Société anonyme dite: (FR) | 1984-02-15 | — | — | EP | claimed |
| US-8043534-B2 | An adhesive comprising a maleimide and an aromatic diene or an aromatic monoene which cure to form useful thermosetting resins for the microelectronic packaging industry; semiconcuctor dies; addition polymerization/Diels-Alder reaction; heat and acid resistance; toughness; noncracking; nondestructive | DESIGNER MOLECULES, INC. (US) | 2011-10-25 | — | — | US | disclosed |
| US-8043534-B2 | An adhesive comprising a maleimide and an aromatic diene or an aromatic monoene which cure to form useful thermosetting resins for the microelectronic packaging industry; semiconcuctor dies; addition polymerization/Diels-Alder reaction; heat and acid resistance; toughness; noncracking; nondestructive | DESIGNER MOLECULES, INC. (US) | 2011-10-25 | — | — | US | disclosed |
| US-20080075965-A1 | Maleimide compositions and methods for use thereof | DESIGNER MOLECULES, INC. | 2008-03-27 | — | — | US | disclosed |
| US-20080075965-A1 | Maleimide compositions and methods for use thereof | DESIGNER MOLECULES, INC. | 2008-03-27 | — | — | US | disclosed |
| US-5001294-A | Synthesis of diaryl alkenes | HAY ALLAN S (CA) | 1991-03-19 | — | — | US | disclosed |
| EP-0054488-B1 | USE OF DI(ALKYLPHENOXY) METHANES AS ISOLATING OILS, AND DI(ALKYLPHENOXY) METHANE WHICH CAN BE USED FOR THIS APPLICATION | COMPAGNIE FRANCAISE DE RAFFINAGE Société anonyme dite: (FR) | 1984-02-15 | — | — | EP | disclosed |
| EP-0054488-A1 | Use of di(alkylphenoxy) methanes as isolating oils, and di(alkylphenoxy) methane which can be used for this application | COMPAGNIE FRANCAISE DE RAFFINAGE Société anonyme dite: (FR) | 1982-06-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080075965-A1 | Maleimide compositions and methods for use thereof | KDM4E, MLLT1, DOT1L | KDM4E 1/4885ALDH1A1 769/4885HTR1A 3739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.